Vaccination

Vaccinating Against Biofilms

CMTX-301 vaccination triggers the body to produce an immune response to the linchpin DNABII biofilm proteins that drive biofilm formation, regardless of pathogen

Vaccinating Against Biofilms

CMTX-301 vaccination triggers the body to produce an immune response to the DNABII linchpin proteins

Targeting Biofilm Structure

Antibodies are produced that target the linchpin proteins, destabilizing the biofilm eDNA structural lattice and thus preventing biofilm development

Targeting Biofilm Structure

Antibodies are produced that target the linchpin proteins, destabilizing the biofilm eDNA structural lattice and thus preventing biofilm development

More Effective Intervention

In the absence of biofilm, bacteria remain vulnerable to immune or antibiotic intervention

  • Increases host clearance of the bacteria
  • Reduces inflammation
  • Reduces potential for bacterial resistance development

More Effective Interventions

In the absence of biofilm, bacteria remain vulnerable to immune or antibiotic intervention

  • Increases host clearance of the infection
  • Reduces potential for bacterial resistance development
  • Reduces inflammation at infection sites